Differential diagnosis-Eosinophilic granulomatosis with polyangiitis (EGPA) or Churg Strauss syndrome

s At the presentation, it was obvious that this patient was
having a multisystem connective tissue disease with neurological involvement.
The main differential diagnosis that were considered were systemic vasculitis due to small vessel vasculitis (eg: ANCA associated GPA, EGPA, MPO or non ANCA associated vasculitis such as IgA vasculitis or cryoglobulinemia),
medium sized vessel vasculitis like PAN or secondary vasculitis due to
Behcet’s or SLE. Transverse myelitis due to any cause (Infections, tumours,
vasculitis) was also a possibility. However primary CNS angiitis was less
likely due to other systemic involvement.